Urology
COMBAT BRS
COMBined Antineoplastic Thermotherapy Bladder Recirculation System
Overview
The Combat BRS System is an innovative bladder recirculation system designed to deliver.
Combat BRS is an innovative bladder recirculation system for the treatment of non muscle invasive bladder carcinomas (NMIBC) with thermotherapy and cytostatic agents such as Mitomycin C, Epirubicin, etc.
The patented system allows an effective heat exchange with a constant temperature of 43 ±0.5 °C, constant pressure and volume flow during the entire treatment period and, for the benefit of the patient, the use of a slim 16 Fr catheter.
Successful in clinical use since 2011, it is safe for patients and medical staff and has a comparable patient tolerability to bladder instillation at room temperature.
3D semi-robotic Arm with integrated electronic-mechanical tracking
The ARTEMIS device differs from others in that it incorporates a semi-robotic mechanical arm with electronic encoders used to scan, digitize and track the prostate in real-time as well as to navigate needles prospectively and precisely.
Several ongoing clinical studies are aimed at demonstrating the clinical evidence of Hyperthermic Intra-VEsical Chemotherapy (HIVEC™):
HIVEC-I HIVEC-II
Prospective, Randomised International Multicentre Clinical Trials in 598 Intermediate Risk NMIBC Patients. HIVEC-I and II have successfully completed recruitment with data release expected in early 2020.
HIVEC-HR HIVEC-R HIVEC-Premito
Further trials encompassing 269 patients are currently evaluating the efficacy of HIVEC at various stages of the NMIBC treatment pathway.
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