ARTEMIS
3D Semi-Robotic Prostate Fusion Biopsy System
Description

ARTEMIS is a pioneer and recognized leader in prostate image guided fusion biopsy and targeted therapy with over 10 years of clinical expertise and persuasive published clinical results.

By compiling Radiology, Urology and Pathology data, the ARTEMIS Fusion Biopsy System has set a new standard in comprehensive prostate care.

In addition to image guided fusion biopsy, the ARTEMIS platform provides applications for further focal therapies, such as HIFU, cryo and brachy treatments.

Easy and fast switching between transrectal and transperineal modules gives urologists the flexibility to choose the preferred biopsy method and to guarantee personalized treatment for each patient.

Fusion of mpMRI with real-time ultrasound images together with semi-robotic, electronic-mechanical tracking of the organ and needles result in clinical advantages not previously possible:

  • significant improvement in the accuracy of prostate biopsy;
  • precise needle navigation to identify lesion;
  • exact reproducing of treatment for analysis and re-biopsy.
PROFUSE RADIOLOGY SUITE
ProFuse
A validated interface between Radiology and Urology guarantees both a precise segmentation of prostate and lesions (ROIs) as well as a quick and easy transfer of Radiology data into the ARTEMIS fusion biopsy system.
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Features
3D semi-robotic Arm with integrated electronic-mechanical tracking

The ARTEMIS device differs from others in that it incorporates a semi-robotic mechanical arm with electronic encoders used to scan, digitize and track the prostate in real-time as well as to navigate needles prospectively and precisely.

Rigid and elastic registration of MRI, PET-CT, PSMA PET-MRI to real-time US images

Enables a high precision fusion as well as elimination of prostate deformation.

Genuine real-time organ tracking and prospective needle navigation

Integrated live tracking of prostate during treatment as well as motion compensation. Real-time, accurate needle navigation and registration. Precise targeting of suspect lesions in reproducible manner.

Current and prior biopsy workflow

Robust, guided workflow for current as well as for prior biopsies. Prior biopsies can be fused with the current plan and compared in order to either analyse or re-biopsy individual points.

SELECTED PUBLICATIONS
March 2018
MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis - PRECISION Study
V. Kasivisvanathan, A.S. Rannikko, M. Borghi, V. Panebianco, L.A. Mynderse, M.H. Vaarala, A. Briganti, L. Budäus, G. Hellawell, R.G. Hindley, M.J. Roobol, S. Eggener, M. Ghei, A. Villers, F. Bladou, G.M. Villeirs, J. Virdi, S. Boxler, G. Robert, P.B. Singh, W. Venderink, B.A. Hadaschik, A. Ruffion, J.C. Hu, D. Margolis, S. Crouzet, L. Klotz, S.S. Taneja, P. Pinto, I. Gill, C. Allen, F. Giganti, A. Freeman, S. Morris, S. Punwani, N.R. Williams, C. Brew‑Graves, J. Deeks, Y. Takwoingi, M. Emberton, and C.M. Moore, for the PRECISION Study Group Collaborators: MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis - PRECISION Study. N Engl J Med 2018; 378:1767-1777
April 2016
Does the addition of targeted prostate biopsies to standard systemic biopsies influence treatment management for radiation oncologists?
Narayanan, R. ; Kurhanewicz, J. ; Shinohara, K. ; Crawford, E.D.: MRI-ultrasound registration for targeted prostate biopsy. EEE International Symposium on Kamrava M, Hegde JV, Abgaryan N, Chang E, Le JD, Wang J, Kupelian PA, Marks LS, University of California, Irvine, CA: Does the addition of targeted prostate biopsies to standard systemic biopsies influence treatment management for radiation oncologists? BJU Int. 2016 Apr;117(4):584-91. doi: 10.1111/bju.13082. Epub 2015 May 4.
March 2016
Relationship Between Prebiopsy Multiparametric Magnetic Resonance Imaging (MRI), Biopsy Indication, and MRI-ultrasound Fusion-targeted Prostate Biopsy Outcomes
Meng X, Rosenkrantz AB, Mendhiratta N, Fenstermaker M, Huang R, Wysock JS, Bjurlin MA, Marshall S, Deng FM, Zhou M, Melamed J, Huang WC, Lepor H, Taneja SS, New York University, New York NY: Relationship Between Prebiopsy Multiparametric Magnetic Resonance Imaging (MRI), Biopsy Indication, and MRI-ultrasound Fusion-targeted Prostate Biopsy Outcomes. Eur Urol. 2016 Mar; 69(3):512-7. doi: 10.1016/j.eururo.2015.06.005. Epub 2015 Jun 22.
December 2015
Magnetic Resonance Imaging-Ultrasound Fusion Targeted Prostate Biopsy in a Consecutive Cohort of Men with No Previous Biopsy: Reduction of Over Detection through Improved Risk Stratification
Mendhiratta N, Rosenkrantz AB, Meng X, Wysock JS, Fenstermaker M, Huang R, Deng FM, Melamed J, Zhou M, Huang WC, Lepor H, Taneja SS, New York University, New York NY: Magnetic Resonance Imaging-Ultrasound Fusion Targeted Prostate Biopsy in a Consecutive Cohort of Men with No Previous Biopsy: Reduction of Over Detection through Improved Risk Stratification. J Urol. 2015 Dec;194(6):1601-6. doi: 10.1016/j.juro.2015.06.078. Epub 2015 Jun 19.
September 2015
Magnetic resonance imaging-targeted biopsy may enhance the diagnostic accuracy of significant prostate cancer detection compared to standard transrectal ultrasound-guided biopsy: a systematic review and meta-analysis
Ivo G. Schoots, Monique J. Roobol, Daan Nieboer Chris H. Bangma, Ewout W. Steyerberg, M.G. Myriam Hunink: Magnetic resonance imaging-targeted biopsy may enhance the diagnostic accuracy of significant prostate cancer detection compared to standard transrectal ultrasound-guided biopsy: a systematic review and meta-analysis. Eur Urol, 2015. 68(3): p. 438-50.
July 2015
Detection of Clinically Significant Prostate Cancer Using Magnetic Resonance Imaging-Ultrasound Fusion Targeted Biopsy: A Systematic Review
Valerio M, Donaldson I, Emberton M, Ehdaie B, Hadaschik BA, Marks LS, Mozer P, Rastinehad AR, Ahmed HU: Detection of Clinically Significant Prostate Cancer Using Magnetic Resonance Imaging-Ultrasound Fusion Targeted Biopsy: A Systematic Review. Eur Urol. 2015 Jul;68(1):8-19.
March 2013
Value of Targeted Prostate Biopsy using MR-US Fusion in Men with Prior Negative Biopsy and Elevated PSA
Sonn GA, Chang E, Natarajan S, Margolis DJ, Macairan M, Lieu P, Huang J, Dorey FJ, Reiter RE, and Marks LS: Value of Targeted Prostate Biopsy using MR-US Fusion in Men with Prior Negative Biopsy and Elevated PSA. European Urology. March 17, 2013.
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