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Dophi IRE – the next-generation irreversible electroporation system

Our focal therapy offering for prostate cancer is expanding.

With the Dophi IRE Electroporation System, we are adding a key modality to our portfolio for the minimally invasive treatment of prostate cancer: irreversible electroporation (IRE). This opens new therapeutic options for urologists and their patients alike.

innoMedicus AG is the exclusive distributor of the Dophi IRE in Switzerland, Austria and Sweden.

The ideal complement to HIFU

HIFU has become an established, minimally invasive treatment option for many patients with localised prostate cancer. But HIFU reaches its physical limits in certain anatomical situations – anterior tumours, calcifications in the acoustic pathway, or tumours in close proximity to critical structures such as the urethra or rectum.

This is exactly where IRE comes in. As a non-thermal modality, electroporation works through short, high-voltage electric pulses that permanently permeabilise the tumour cell membrane – while largely preserving the surrounding extracellular matrix, nerves, vessels and sphincters.

Tumours that are physically out of reach for HIFU can in many cases be treated precisely and gently with IRE.

Comprehensive focal therapy from a single source

With HIFU and IRE, we offer urologists an aligned therapeutic portfolio that enables individual, tumour- and patient-specific treatment planning.

The goal remains the same: maximum oncological control with the best possible preservation of quality of life – in particular continence and erectile function.

Key benefits at a glance

  • Non-thermal ablation – largely sparing vessels, nerves and sphincters
  • Reaches tumours physically inaccessible to HIFU – anterior location, calcifications, critical adjacent structures
  • Real-time multi-parameter monitoring – continuous oversight throughout the procedure
  • Built-in ECG synchronisation module – for enhanced patient safety
  • Flexible probe configurations (2 to 6 probes) – for tailored ablation geometries

Also for interventional radiology: liver and pancreas

The Dophi IRE is not limited to urology. In interventional radiology, the system is equally suited for soft-tissue ablation in anatomically complex regions – in particular liver tumours adjacent to the portal vein, hepatic veins or bile ducts, as well as locally advanced pancreatic cancer, where thermal modalities are often ruled out due to surrounding vessels and nerves.

This makes the Dophi IRE a precise, non-thermal treatment option for interventional radiologists as well – covering indications that have been difficult to address with conventional ablation methods such as RFA or MWA.

Would you like to learn more about our expanded focal prostate therapy portfolio, or about the use of the Dophi IRE in interventional radiology? We look forward to hearing from you:
welcome@innomedicus.com

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